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Sheep nasal mucosa was used for ex vivo permeability studies and revealed that RH-PLGA/chitosan increased RH permeability by 3.22-fold compared to RH-PLGA nanoparticles

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NRF2 depletion exacerbates IMQ-induced psoriasis-like symptoms and negates the therapeutic effect of SFN To further investigate the mechanism of SFN, we utilized both wild-type and NRF2-deficient mice for modeling and treatment