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We hypothesized that disrupting this tether or lengthening the linker that connects the two -CTs may uncouple the two binding sites in the active state of IGF1R, reduce the negative cooperativity, and allow the binding of the second IGF1

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doi: 10.1111/dom.12824 10 ZaazoueeMSHamdallahAHelmySKHasaboEASayedAKGbreelMIet al

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Some authors have shown an increase in endogenous antioxidant enzymes after exogenous SODs administration