Because of its wide reaching effects in the body Vitamin B12 deficiency has been linked to increased risk of cardiovascular disease, dementia, cancer, depression and osteoporosis
238 , 239 , 240 According to the Centers for Disease Control and Prevention (CDC), in 2020, people age 75 and older had the highest numbers and rates of TBIrelated hospitalizations and deaths, accounting for about 32% of TBIrelated hospitalizations and 28% of TBIrelated deaths
Cells release chemical messengers including interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and various prostaglandins
volatile organic compounds (VOCs) like chloroform
It is also possible that HPA sensitivity rather than HPA axis dysfunction exists in patients (63)
Examples of biologics used in the treatment of psoriasis include adalimumab (Humira), etanercept (Enbrel), infliximab (Remicade), ustekinumab (Stelara), and secukinumab (Cosentyx) (Armstrong 2014