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10.1039/d2fo01075e Summary Keywords diabetes mellitus, natural polysaccharide, oxidative stress, metabolism, mechanism Citation He L-Y, Li Y, Niu S-Q, Bai J, Liu S-J and Guo J-L (2023) Polysaccharides from natural resource: ameliorate type 2 diabetes mellitus via regulation of oxidative stress network

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Tirzepatide is a dual GIP/GLP-1 receptor agonist, meaning it activates two hormonal pathways involved in appetite regulation and blood sugar control

However, when GLP-1 are used in combination with other hypoglycemic drugs such as insulin, sulfonylureas, etc., the risk of hypoglycemia may increase

It further suppressed the expression of cell-cycle-associated proteins, such as Ki67 and cyclin D1, resulting in inhibited tumor growth

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