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During aging, metabolic function gradually declines, leading to insulin resistance, fat accumulation, and insufficient energy metabolism

The species results of these two methods were cross-compared and a result was only considered definitive if it was identified using both methodologies

doi: 10.3389/fphar.2025.1602976 Received 30 March 2025 Revised 13 November 2025 Accepted 14 November 2025 Published 19 December 2025 Volume 16 - 2025 Edited by Bernd Rosenkranz, Fundisa African Academy of Medicines Development, South Africa Reviewed by Kacper Nijakowski, Poznan University of Medical Sciences, Poland Miriam Njoki Karinja, Science for Africa Foundation, Kenya Updates Copyright 2025 Mazur, Ndokaj, Salerno, Vallone, Ardan, Bietolini, Carrouel, Wilk, Sarig, Ottolenghi and Bourgeois

Prepping for an Intramuscular Shot An intramuscular (IM) injection delivers vitamin B12 directly into a muscle, usually in the upper arm, thigh, or upper buttocks

Injections are no fun, especially if they leave you with a nasty bruise for days afterward

Any discomfort typically subsides quickly