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Publisher Current Reviews in Musculoskeletal Medicine Accessed Jun 27, 2026 Study type Systematic Review Limitations: Narrative reviews synthesize existing literature

The presence of pyrrolizidine alkaloids in BP can create severe conditions of lung cancer and hepatotoxicity, which are strongly related to the botanical origin of BP

When it becomes overactive, underactive, or dysregulated, symptoms can appear anywherefatigue, digestive issues, joint pain, rashes, neurological changes, hormonal instability, and chronic inflammation

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Alessi DR, Sammler E (2018) LRRK2 kinase in Parkinsons disease

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