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Liraglutide treatment improves endothelial function in the Ldlr / mouse model of atherosclerosis and affects genes involved in vascular remodelling and inflammation

(2025) Zepbound (Tirzepatide) injection (2025) Ania M

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In this trial, MASH resolution without worsening of fibrosis was achieved in 4462% of participants receiving tirzepatide, compared with 10% in the placebo group, and fibrosis improvement of at least one stage without worsening of MASH occurred in up to 55% of tirzepatide-treated individuals versus only 30% with placebo [81]

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