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Routine monitoring of serum calcitonin or using thyroid ultrasound is of uncertain value for early detection of MTC in patients treated with RYBELSUS Important Safety Information for RYBELSUS WARNING: RISK OF THYROID C-CELL TUMORS In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures

Sci Rep 7(1):9100

Perifollicular capillaries regress as the follicle shrinks, starving remaining cells of oxygen and nutrients

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Lyophilized (freeze-dried) peptide should be stored at minus 20 degrees Celsius (minus 4 degrees Fahrenheit) for long-term storage