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Atherosclerosis is a multifaceted pathological process that progresses through several stages, beginning with the retention and oxidation of low-density lipoprotein (LDL) within the arterial intima, which triggers a localized inflammatory response

Our study revealed for the first time that yohimbine administered to HFD-induced obese rats at a dose of 5 mg/kg for 30 days was able to alleviate oxidative stress and diminish the elevated concentration of sulfate, probably by induction of TST expression

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