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Lim VM, Do A, Berger TG, Nguyen AH, DeWeese J, Malone JD, Jordan K, Hom F, Tuffanelli L, Fillari P, Siu S, Grossman R (2016) A decade of burn unit experience with Stevens-Johnson syndrome/toxic epidermal necrolysis: clinical pathological diagnosis and risk factor awareness

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So, this cascade disabled the cell capacity to convert toxic lipid hydroperoxides (L-OOH), such as malondialdehyde (MDA) and 4-hydroxy-trans-2-nonenal, into less-toxic lipid alcohols (L-OH) and culminated in cell death from lipid peroxidation