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Joseph Volpicelli, a psychiatrist and addiction-medication researcher in Pennsylvania, the drug can also affect the brain's reward circuit, dulling the dopamine hit someone might otherwise get from a greasy french fry or dirty martini

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Bezin J, Gouverneur A, Penichon M, Mathieu C, Garrel R, Hillaire-Buys D, et al

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Using single-sample GSEA, we assigned each patient an OxPhos score using the Molecular Signatures Database (MSigDB) Hallmarks Oxidative Phosphorylation signature 39,40 and then split patients based on the cohort mean (Fig