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10.1016/s2213-8587(22)00187-5 22 KambleN

DOI: 10.1093/neuros/nyab021 48

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These constraints can be mitigated by anchoring point-of-care readouts to validated lab assays, implementing specificity controls (e.g., SOD/catalase for O 2 /H 2 O 2 , chelators for Fenton dependence), and using compartment-targeted, ratiometric reporters with documented calibration (Krl and Brzenicki 2023

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