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Decreased food intake and body weight in pancreatic polypeptide-overexpressing mice

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Weight loss independently improves blood sugar levels

The full data are due at a medical meeting and in a peer-reviewed journal later in 2026

In animal models of psychosis, liraglutide administration consistently led to a reduction of psychotic-like behavior 119,120,121 , which was also associated with increased brain-derived neurotrophic factor, CREB/p-CREB, and Trk-B expression in the hippocampus and prefrontal cortex 120 , and reduced serum and hippocampal tumor necrosis factor and oxidative stress 121