A recent report from the Institute for Clinical and Economic Review, an independent nonprofit that evaluates the value of medical treatments, found that GLP-1s such as Ozempic, Wegovy and Zepbound are cost-effective, meaning the medications health benefits justify their price
The research from the clinical trials is promising
34 A prospective, singlearm, multicentre study in Japan, evaluating 58 patients who switched from exenatide twice daily to exenatide ER, observed improved glycaemic control (HbA 1c decrease of 0.2%point over 24 weeks)
Beyond weight, the trial showed meaningful reductions in systolic blood pressure, knee pain, and improvements in cardiovascular markers including non-HDL cholesterol and triglycerides
Start Retatrutide first, establish your baseline response over 2 to 4 weeks, then layer in MOTS-C
They also affect hunger and digestion