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GE2 treatment significantly reduced IL-13 levels in the dorsal hippocampus compared to vehicle (main effect of treatment: F (1,44) = 5.346, p 2 = 0.106, p = 0.025

While the long-term prognosis for full recovery is uncertain, the medical profession remains hopeful for a better understanding

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What has changed is not the feasibility of developing drugs without complete biological knowledge, but the expectation that developers be transparent about what is and is not known, and that uncertainty be actively managed rather than minimized (ICH E9 guidance

A., & Meier, J