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NNMTs role is to transfer a methyl group to nicotinamide (vitamin B3), creating 1-methylnicotinamide a reaction that consumes cellular methyl donors and depletes nicotinamide adenine dinucleotide (NAD) stores
Pawlak and others reviewed studies of B12 deficiency among vegetarians and vegans using serum B12 (Pawlak, 2014) as well as methylmalonic acid and holotranscobalamin (Pawlak, 2013)
Applications in Research As a molecular tool to study growth hormone fragmentspecific signalling mechanisms
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