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2 There is an important mechanistic interdependence here that is easy to miss

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using 1,200 mg doses showed only 37.5% efficacy versus 18.7% placebo, with 32% of patients experiencing adverse events including liver dysfunction

Experimental studies demonstrate that metastatic PCa-derived EVs enhance malignant phenotypes by stimulating cancer cell proliferation, migration, and invasion while suppressing apoptosis [53]

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