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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of medications originally developed for managing type 2 diabetes

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Polymorphisms in MTHFR (most commonly C677T and A1298C) can reduce this enzymes efficiency, leading to lower methylfolate levels and impaired methylation

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Creatine helps supply muscles with energy by increasing stores of phosphocreatine at the beginning of activity, recycling the stores of phosphocreatine after exercise, increasing glycogen storage in muscles and preventing lactic acid build up

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