These were dose-dependent and typically transient
at the same time, it can suppress appetite, enhance satiety and promote fat metabolism, helping overweight or obese people achieve weight management
Osteoporos Int 30(8):17091710 Thomas MK, Nikooienejad A, Bray R et al (2021) Dual GIP and GLP-1 receptor agonist tirzepatide improves beta-cell function and insulin sensitivity in type 2 diabetes
The guidance is in response to recent case reports and large case series that have shown a risk of retained gastric contents and cases of pulmonary aspiration during sedation for endoscopic procedures or general anaesthesia in individuals treated with GLP-1RAs or GLP-1/GIPRAs
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Plus, rapid weight loss associated with GLP-1s may contribute to gallstone formation, while the emotional and psychological impacts of sudden changes in appetite and body composition remain unstudied