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Treatment is offered only when clinically appropriate, with ongoing supervision to support patient safety

The Keap1-Nrf2 pathway: mechanisms of activation and dysregulation in cancer

DerwallMMalhotraRLaiCSBeppuYAikawaESeehraJSet alInhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis

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For example, it has been found that polydatin promotes mitochondrial biogenesis and protects against mitochondrial oxidative stress via the activation of Sirtuin-1-PGC-1 pathway and Sirtuin-1-Nrf2-ARE pathway in kidney diseases (Huang et al., 2015

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