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Llorente, M
This is why the two are often combined (Nat Rev Urol, 2025)
As NO reacts with superoxide anion O2 -faster than the rate of dismutation and inactivation of O2 - by superoxide dismutase (SOD), this concentration of SOD can be a significant determinant of the NO bioactivity (Reference Faraci and Didion83)
URL: Russell-Aulet M, Dimaraki EV, Jaffe CA, DeMott-Friberg R, Barkan AL
Even controlled micro-injury can trigger aberrant scar formation in genetically predisposed individuals
thus, studies are proposed to have a duration of 6 months to allow the detection of clinically meaningful changes in bone structure (by DXA or other imaging modalities) (Reference Zibellini, Seimon and Lee7)
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