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A 33-year-old female presented a painless pigmented dark-brown macule, with evolution time of two years, on palatine attached gingiva of maxillary right first molar, and measured 0,6 cm in maximum diameter (Case 3)

doi: 10.1002/art.34339 45 CrottiCAgapeEBeccioliniABiggioggeroMFavalliEG

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Moreover, inflammatory markers IL-1 and TNF- decreased by 30 %, demonstrating measurable anti-inflammatory action