In an intervention study on meal sequence, individuals with prediabetes were instructed to consume GLP-1-stimulating foods, such as meat, fish, or salad, at the beginning of a meal, followed by a 5-min waiting period before consuming carbohydrate-rich foods, such as rice or bread
The appetite suppression from GLP-1 medications combined with fasting rules creates a framework that some individuals with eating disorder history find reinforces restriction-based thinking
Metabolic Rebound and Appetite Dysregulation After Stopping Your metabolism doesn't simply return to its pre-treatment baselineit often overshoots into a hyperappetitive state
Instead, the weight loss achieved in the clinical trials was the result of months of support from doctors, dietitians, physical activity advisors, nurses etc
Some clinicians also explore microdosing tirzepatide for inflammation benefits rather than purely for weight loss, which involves even lower doses with less GI impact
K.McbrideS