According to the FDA, GLP-1s are approved for people with obesity (BMI of 30 or higher)
The expression of IL-17A, Bax, caspase-3 and ROS, up-regulated the expression of p53, Bcl-2, Nrf2, HO-1, NQO-1, SOD (Li et al., 2020)
DEXA scans from 189 participants reveal that 62% to 69% of total weight lost on retatrutide came from fat mass, not muscle
GLP-1 is an incretin hormone secreted by L-cells in the small intestine in response to nutrient intake
This phylogenetic analysis of matched primary melanomas and their regional and distant metastases showed patterns of parallel metastatic dissemination and reseeding among different tumour deposits
From a public health perspective, the widespread implementation of microbiome-targeted therapies could alleviate the burden of obesity and depression, two prevalent conditions with significant societal and economic costs