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A280 was measured via UV-Vis spectroscopy in a 0.1 mm Quartz cuvette, and protein concentration was calculated from A280 via Beers law using the extinction coefficient calculated from protein sequence via ExPasy ProtParam

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Across n=95 trial participants, the authors reported over 20 weeks a weight reduction of -15.7 percent (cagrilintide 1.2 mg) and -17.1 percent (cagrilintide 2.4 mg) in combination with semaglutide 2.4 mg, compared with -9.8 percent on semaglutide alone