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Perhaps recklessly, Im going to suggest that a comparison might be drawn to medicinal cannabis

B12 is naturally present in animal based foods such as: Chicken and lean red meat Fish and seafood such as oysters, clams, salmon, tuna and catfish Dairy products such as milk, cheese, yoghurt, plus vegan milk substitutes that are fortified Eggs Plus, fortified breakfast cereals

Neither approach shows a meaningful difference in outcomes

Horses: 5-10mL

Potency Test This test measures the strength or concentration of an active pharmaceutical ingredient (API) over time, ensuring the medication maintains its potency until its beyond-use date when used with stability testing.

Vitamin B12 is considered beneficial and generally safe, even at high doses