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Bioavailability is higher, though the rapid peptidase degradation still limits systemic peptide exposure

Intramuscular injection into the vastus lateralis (thigh) is anatomically feasible but less commonly used due to patient accessibility and comfort

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Structural and pharmacological studies demonstrate that Cagrilintide binds these receptor complexes with high affinity in a manner that resembles endogenous amylin while incorporating modifications that increase peptide stability and prolong receptor engagement [2]

BPC-157 is a stable pentadecapeptide composed of fifteen amino acids

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