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M.Rios-CovinD.ArboleyaS.GueimondeM.et al (2020)

Just the levels of quinine found in tonic water may cause potentially fatal immunologically-mediated hypersensitivity reactions, basically like allergic reactions, where it interacts with antibodies to trigger autoimmune reactions that can include chills, fever, a drop in blood pressure, painful bluish discoloration of the hands and feet, and clotting within your blood vessels

The most reliable non-laboratory indicator is reduced effectiveness, weaker appetite suppression or slower results despite consistent dosing

Over time, this leads to a brighter, more radiant complexion with reduced pigmentation

Science 353(6307):1514

Zepbound is only approved for adults 18 and older