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Ironically, many women with PCOS report improved energy over time on tirzepatide

Notably, inhibition of de novo lipogenesis reduces NADPH consumption and protects cells from glucose starvation 26,32

Furthermore, mediation analysis of AIP with PFOA, PFOS and PFNA, revealed that the suppression effects mediated by RBC folate were 16%, 25%, and 10%, respectively

Statistical analyses were performed using SPSS ver

Ethics statement The studies involving humans were approved by the local ethics committee of Iran University of Medical Sciences approved the research protocol in accordance with the ethical code IR.IUMS.FMD.REC.1401.570

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