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It directly upregulates COL1A1, COL1A2, and COL3A1 at the mRNA level in human skin fibroblasts (quantified by qRT-PCR and northern blot), increases collagen protein synthesis (measured by [H]-proline incorporation into hydroxyproline-containing collagen peptides by Sircol assay), and promotes lysyl oxidase activity (copper-dependent cross-linking collagen fibrils for tensile strength)

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Neuropsychobiology, 9 (4), 197-206

Generally, individuals who struggle with low energy, slow metabolism, or weight management issues may benefit

I generally take a magnesium/potassium combo supplement, along with folate (400 to 800 mg a day) , and vitamin D