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Although RID is an imperfect measure with various limitations, the researchers modified standard RID calculations to include parameters for bioavailability and long-acting formulation

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Dawson EB, Evans DR, Harris WA, Teter MC, McGanity WJ

Figure 3 5.1 Epigenetic regulatory mechanisms EED exposure fundamentally alters the epigenetic landscape through modifications to DNA methylation patterns, histone modifications, and non-coding RNA expression profiles, creating molecular changes that persist across generations and potentially affect offspring health in unprecedented ways