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Mant CT, Chen Y, Hodges RS

Targeted agents like 5-HT4 agonists (tegaserod, prucalopride), guanylate cyclase-C agonists (linaclotide), and NHE3 inhibitors (tenapanor) modulate motility and pain signaling but face limitations such as side effects (e.g., diarrhea, cardiovascular risks) or insufficient long-term data

b , Gross appearance of E12.5 embryos of the indicated genotypes

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