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5.4 Effect of PCs on diabetic complications 5.4.1 PCs and diabetic nephropathy Diabetic nephropathy (DN) is a primary microvascular complication of diabetes mellitus, characterized by proteinuria, glomerular enlargement, reduced tubular filtration, renal fibrosis, and renal dysfunction, ultimately leading to end-stage renal disease (Samsu, 2021)

There is also evidence that alpha-lipoic acid can improve the function and conduction of neurons in diabetes

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inflammatory bowel disease (IBD)

The standard dosing schedule involves gradual titration specifically to enhance tolerability

Then, through the catalytic action of GR, GSSG is reduced back to GSH, achieving its regeneration and sustained antioxidant effect