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SAM and methyl-donor pools laboratory work has tracked changes in cellular SAM, SAH and 1-methylnicotinamide levels following NNMT inhibition

Now Novo Nordisk has unveiled Phase 3 data for cagrilintide, its long-acting amylin analog

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The global DNA methylation in the livers of HFD-fed mice was increased, with significant gene-specific hypermethylation of CYP2R1, CYP27A1, CYP27B1, and VDR, and hypomethylation of CYP24A1

Umeno A, Biju V, Yoshida Y