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The introduction of this new indication may have led to a broader user population, consequently resulting in a higher number of reported adverse reactions

Dietary nitrates and nitrites , found in foods such as beetroot and leafy greens, can be converted to NO and have shown promising results in improving vascular function and lowering blood pressure

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Additionally, we explore natural compounds and extracts studied for their antioxidant properties, offering potential therapeutic avenues for managing free radical-induced damage

NICE NG28 recommends DPP-4 inhibitors as add-on therapy in type 2 diabetes management, or as an alternative first-line option if metformin is contraindicated or not tolerated

Treatment choice depends on individual clinical evaluation by a licensed provider