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These include regulation of mechanisms controlling reactive oxygen species (ROS), which cause macromolecular damage 16,17 , mitochondrial turnover or mitophagy 18 , and the mitochondrial unfolded protein response (UPR mt ), in which mitochondrial damage can be prevented by the removal of aggregated or unfolded proteins 19

Weekly reminders on your injection schedules

There is no FDA-approved combination of the two, but there are no known direct drug interactions either

Retatrutide simulates three gut hormones: GLP-1, GIP and glucagon

Both support weight loss with compounded GLP-1s

This is a general guideline, and your dose will be based on how well youve tolerated Mounjaro, any side effects youve experienced and your individual goals