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2019;21(Suppl 1):72-81

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Other in vitro studies suggest that gliadin itself increases intestinal permeability indirectly by promoting the release of zonulin, a protein that induces TJ disassembly and is present in the submucosa of active coeliac patients at concentrations sixfold greater than healthy controls (Fasano et al

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The data showed that two of the most common mistakes were taking the medication daily instead of weekly and starting immediately with the highest dose instead of following the recommended step by step schedule