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A rare human variant that disrupts GPR10 signalling causes weight gain in mice

Psychiatry, 13 , 611616

Because of their relatively small size, approximately 10-20 kDa or less than 5 nm in size, aptamers eliminated from the blood very fast after in vivo administration

Digital treatment ranked second, applied in 57 trials (21.8%), followed by long-term care management in 54 trials (20.6%)

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Le peptide agit principalement via la modulation de la voie du facteur de croissance endothlial vasculaire (VEGF) et du systme NO