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223 Under hypoxic pressure, autophagy orchestrates selective degradation of cellular components, including mitochondria (mitophagy), ER (ER-phagy), lipid droplets (lipophagy), ribosomes (ribophagy), nuclei (nucleophagy), and peroxisomes (pexophagy), 224,225,226,227 thereby sustaining tumor metabolism and viability

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rather, it represents the synthesized active binding fragment of a much larger, naturally occurring 43-amino-acid protein known as Thymosin Beta-4 (T4)

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