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The Thermo Scientific LC3 Detection Kit (ThermoFisher, Waltham, MA) was employed to stain native LC3 based on the manufacturers protocol

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This broad-spectrum neutralization halts the chain reactions of oxidative damage that destroy cellular proteins and mutate DNA

Metformin also improved mitochondrial functioning (AMPK) in fibromyalgia muscle cells

Blocking NNMT preserves the NAD+ precursor pool (1.2-1.6x increase in intracellular NAD+), increases SAM availability for epigenetic methylation, and activates SIRT1/SIRT3 signaling

In cases of gastric ulcers and damage to the liver caused by toxins, BPC-157 has demonstrated protective effects