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High performers people with demanding cognitive and physical loads often have the greatest need for deep sleep and the greatest disruption to it

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These may include: muscle relaxants, narcotics, pain medications (NSAIDs), antihypertensives, antiarrhythmics, diuretics, drugs that speed up gut motility, antibiotics, antidepressants, and others

Finally, the relationship between GSH and the immune system was clearly demonstrated in a large study which showed that children with autistic disorder universally have lower natural killer cell activity in peripheral mononuclear cells than those without the disorder which correlated with low intracellular levels of GSH as shown in Table 10[79]

For example, a 2013 trial found it significantly improved menopause symptoms across multiple categories, including vasomotor, physical, and psychological measures.62 While its primarily studied for menopause, theres some evidence suggesting it may also help with PMS-related discomfort.53 Chasteberry (Vitex) Pycnogenol In a 2011 study, perimenopausal women who took Pycnogenol for two months experienced statistically significant reductions in hot flashes, night sweats, mood swings, irregular periods, reduced libido, and vaginal dryness.9 For PMS symptoms, a 2008 study found Pycnogenol significantly lowered menstrual pain in those with dysmenorrhea.63 Wild yam Wild yam has a long history of traditional use for menopausal and inflammatory symptoms

Use: Consumeone tablespoon (15ml) per day, directly or mixed with water or your favorite beverage