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Greydanus DE, Cabral MD, Patel DR

First, a large proportion of evidence still comes from preclinical animal studies, which, while informative, may not fully replicate human physiological complexity

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lim-7p::gfp reporter strain lim-7 promoter was amplified by PCR from the lim-7p::sdn-1::gfp::tbb-2UTR (see above) plasmid using primers CGACTCTAGAGGATCAGTACTTGTGCCTTGATTCTCCTG and TCATTTTTTCTACCGCCAATCGACAGCCGGCAC

Body composition begins shifting favorably, with preserved or even slightly increased lean mass despite ongoing weight loss