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While this effect is often considered beneficial in research contexts, it necessitates careful tracking to prevent too much glucose lowering, very in subjects with already normal insulin response

Immunology (2015) 144:7990

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All weight loss injections carry some risk of nausea, though rates vary from 24-44% depending on the medication and dose

A numbing agent may be applied to minimize discomfort

Study: Trajectory of weight regain after cessation of GLP-1 receptor agonists: a systematic review and nonlinear meta-regression