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Evidence comes mainly from preclinical models and limited human studies

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Actions of GLP-1 on exocrine pancreas Infusion of GLP-1 to mimic postprandial levels inhibits pancreatic exocrine secretion in response to intragastric infusion of a liquid meal in man (127)

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Endocrinology 153(3):15381547 Mansoor H, L BA, Morten D, Kathleen D, G EF, R FD et al (2019a) Oral Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

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For a clinician-facing summary of timing and management considerations see this safety review

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