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Obesity programs that include psychological support in addition to medication tend to fare better

When you eat, your intestines release GLP-1, which signals your pancreas to produce insulin, slows how quickly food leaves your stomach, and communicates with your brain to reduce appetite

When those receptors are stimulated more persistently, GI effects intensify

This hormone stimulates insulin release from the pancreas, suppresses glucagon secretion, slows gastric emptying, and acts on the brain to reduce appetite

Tirzepatide represented the second generation of this research, introducing a unimolecular dual agonist approach

Furthermore, the same authors studied the effects of GLP-1 receptor stimulation on the proliferation of human pancreatic adenomcarcinoma cell lines and found no growth-promoting effects (19)