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This anabolic effect is the primary reason GH secretagogues have attracted interest in age-related sarcopenia and frailty

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124,126 The reduction in IIS activity in the intestine can almost double the lifespan of nematodes without affecting development and reproduction

Surprisingly, a slight improvement in change of peak oxygen consumption (peak VO 2 ) was observed in the albiglutide group compared with placebo (mean 0.9 0.5 ml/kg/min versus 0.6 0.5 ml/kg/min