gip y glp 1 LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept: Cell Metabolism Frontiers | Mechanisms of action

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Discussion Our research aimed to design and perform computational analysis of the fusion proteins with high affinity and specificity for human serum albumin and a protease-resistant GLP-1 peptide to produce potent GLP-1 agonists with an extended plasma half-life for the treatment of type 2 diabetes

Pedersen WA, McMillan PJ, Kulstad JJ, Leverenz JB, Craft S, Haynatzki GR

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[1] The prescribing clinician or diabetes specialist nurse should be consulted to confirm the appropriate timing and dosing for individual patients, particularly those with complex medical histories or those who experienced surgical complications