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In AP, however, this finely tuned system shifts toward pathological oxidative stress, with disturbed redox homeostasis promoting excessive ROS production and propagation of organellar injury in PACs ( Mitochondria are a major intracellular ROS source in AP, particularly at complexes I and III of the ETC

Significant differences among groups were evaluated by one-way analysis of variance (ANOVA), followed by the Tukey's post-hoc tests

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This antioxidant, known as glutathione, is a tripeptide composed of three amino acids: cysteine, glutamate, and glycine