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The low IGF-I levels is caused by nutritionally acquired hepatic GH resistance from intra-portal hypoinsulinemia ( Table 1

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Torres KE, Zhu QS, Bill K, Lopez G, Ghadimi MP, Xie X, et al

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The UKs National Institute for Health and Care Excellence and European Medicines Agency approved dapagliflozin as an adjunctive treatment of type 1 diabetes in 2019 and 2018, respectively [26, 27]

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