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Preclinical evidence in transgenic models of Alzheimers disease suggests that liraglutide exerts neuroprotective effects by reducing amyloid oligomers, normalizing synaptic plasticity and cerebral glucose uptake and increasing the proliferation of neuronal progenitor cells, Paul Edison, MD, PhD, lead study author and professor of neuroscience at Imperial College London, and colleagues wrote

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These effects suggest potential cognitive benefits and brain health preservation (Figure 3)